Thermo LTQ Velos Pro Orbitrap Elite

Orbitrap-based mass spectrometers are an essential tool in many proteomics labs. The enhanced power of the Orbitrap Elite instrument enables new standards of performance for multiple proteomics applications.

The Thermo Scientific Orbitrap Elite hybrid mass spectrometer raises the bar for MS and MSn performance and versatility by combining our premier dual-pressure linear ion trap mass spectrometer with a novel high-field Orbitrap™ mass analyzer. The system delivers greater than 240,000 resolution (FWHM), increased sensitivity, high scan speeds and a larger dynamic range.

High-field Orbitrap mass analyzer for ultrahigh-resolution
The high-field Orbitrap mass analyzer geometry and advanced signal processing technologies enable resolution of >240,000 FWHM, a 4x increase over previous technology. This ultrahigh resolution is especially useful when analyzing samples of high complexity and targeting analytes of low abundances in applications such as proteomics, metabolomics and lipidomics.

Faster scanning for UHPLC compatibility
The high-field Orbitrap geometry and advanced signal processing also provide an up to 4x improvement in scan speed, making the Orbitrap Elite system more compatible with narrow chromatographic peaks from UHPLC separations.

Higher sensitivity for complex samples
Innovations in pre-amplifier electronics improve sensitivity. Paired with the ultrahigh-resolution, they provide more comprehensive data and a deeper look into complex samples.

Fragmentation options increase versatility

In addition to traditional collision-induced dissociation (CID), the Orbitrap Elite mass spectrometer features higher-energy collisional dissociation (HCD) that provides superior fragmentation and higher-quality MS/MS spectra for many types of samples. Optional electron transfer dissociation (ETD) preserves labile post-translational modifications of proteins. Intelligent data-dependent decision tree (DDDT) logic can combine multiple fragmentation techniques in a single analysis to significantly improve proteome coverage.

The Orbitrap Elite mass spectrometer can analyze complex samples at a greater depth than ever before, helping scientists meet the most demanding challenges in proteomics, metabolomics, lipidomics and metabolism.

A quantum leap in Orbitrap MS performance:

Key features of the Orbitrap Elite system:

• High-field Orbitrap mass analyzer for higher mass resolution and higher scan speed
• Advanced signal processing for higher resolution
• Improved ion optics for efficient ion injection into the Orbitrap
• New Orbitrap image current pre-amplifier for higher sensitivity
• Velos Pro linear ion trap generation II ion optics with neutral blocking technology for increased robustness

The Thermo Scientific Velos Pro is the pinnacle of ion trap mass spectrometry that delivers enhanced performance for complex sample analyses. A novel wide dynamic range discrete dynode detection system offers the ultimate in identification and quantitation of low-abundance compounds and provides absolute confidence in every result. For the first time ever with an ion trap, the Velos Pro offers TrapHCD (Higher-Energy Collisional Dissociation) combined with CID (Collision-Induced Dissociation), PQD (Pulsed-Q Dissociation) and ETD (Electron Transfer Dissociation) to solve the most difficult analytical problems.

Fast, Sensitive and Fully-Featured

• Wide dynamic range discrete dynode detection system provides up to six orders of linear quantification
• Trap-HCD with CID, PQD and ETD, produce abundant structural information for compound identification
• Unique dual-pressure linear ion trap increases sensitivity, scan speed and mass resolution
• Proprietary S-lens ion optics increase ion transmission and shorten trap fill time, improving instrument sensitivity and speed
• Generation II ion optics improve robustness, reducing downtime
• Predictive automatic gain control reduces cycle times, speeding analyses

Supports the Most Sophisticated Applications

• Characterization and identification of proteomics samples with maximum coverage using complementary dissociation techniques
• Relative protein quantification using isobaric labelling techniques
• Absolute protein quantification using AQUA peptides
• Identification and quantification of complex drug metabolism samples

Mass Range
15 to 200m/z
MS Scan Power
MSn
Resolution
0.3 FWHM
Voltage
230V
Weight (Metric)
120kg

KRSS Ltd offer high-quality pre-owned Mass Spec, LCMS, GCMS, HPLC and GC systems allowing affordable entry into a rapidly developing market.

All KRSS instruments are thoroughly inspected by manufacturer trained engineers (including all components and parts), cleaned and decontaminated, completely refurbished (defective parts and components are replaced with genuine parts), serviced and bench-tested to ensure the equipment meets the manufacturers original specifications - this guarantees quality, performance and reliability at a fraction of the OEM costs.

With over 50 instruments in stock, covering all major manufacturers KRSS has systems for a variety of application requirements. All instruments are supplied with a comprehensive warranty and optional service contracts to ensure trouble-free operation.